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Hand holding Hydration Room Glutathione nasal spray bottle on a solid blue studio background.

Glutathione Nasal Spray

Glutathione is your body's primary antioxidant — supported daily. Compounded fresh in our CA pharmacy, formulated for nasal absorption. Refrigerate after opening · 60-day BUD.

For adults 18+. A clinical consult is required before purchase.

$125/mo or $155 one-time purchase
  • What's in it & how it works

    Reduced L-Glutathione (GSH) at 120 mg per dose — the active form your cells use directly. Intranasal delivery bypasses the digestive tract, where most oral glutathione is degraded before it can reach circulation.

  • Ingredients

    Reduced L-Glutathione (GSH) in a sterile saline-based intranasal vehicle with a permeation enhancer. Compounded in a PCAB-accredited facility by licensed providers. (Full ingredient list pending ops sign-off.)

  • Shipping & storage

    Cold-chain shipping is available only where Hydration Room and its pharmacy partners can legally dispense compounded prescriptions. Refrigerate after opening — 60-day beyond-use date.

  • Disclaimers

    Glutathione nasal spray is a compounded prescription medication. A licensed Hydration Room provider must determine whether it is appropriate based on your medical and family history. Restrictions apply.

Glutathione Nasal Spray Clinic-grade daily spray · from $125/mo

How it works

Why nasal delivery.

  1. Absorption at the source

    The nasal lining contains a dense network of blood vessels, allowing certain compounds to be absorbed without passing through the digestive system first.

  2. Designed to bypass digestion

    This delivery method is designed to avoid breakdown in the gut and liver, supporting efficient use of each dose.

  3. Used by the body

    NAD+ and glutathione play important roles in cellular processes, including energy metabolism and antioxidant activity.

Why you'll love the spray

Antioxidant Activity

Helps maintain antioxidant balance*

Cellular Health

Plays a role in cellular health*

Mitochondrial Function

Involved in mitochondrial function*

Immune Support

Contributes to normal immune function*

Detox Support

Supports natural detox processes*

Metabolic Support

Helps maintain normal metabolic function*

How to Use

  1. Remove Cap

    Remove the protective cap from the spray bottle.

  2. Prime Pump

    If first use, prime with 2-3 test sprays into the air.

  3. Tilt Head

    Tilt head slightly forward and insert nozzle into nostril.

  4. Spray

    2 sprays per nostril, twice daily.

  5. Build Your Routine

    For those who want consistent results, this becomes part of their routine.

One bottle. 30 days. From our clinic to your home.

Subscribe & save 20%. Keep your antioxidant baseline stocked between clinic visits.

  • Same Reduced L-Glutathione (GSH) used in our clinic IV pushes
  • Cold-chain delivery, free shipping on every refill
  • 30-day money-back guarantee
  • HSA / FSA-eligible

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NAD+ Nasal Spray + Glutathione, paired into one daily ritual.

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Frequently asked questions about Glutathione nasal spray

Ask a nurse
  • What is glutathione?

    Glutathione is a tripeptide — three amino acids (glutamate, cysteine, glycine) — that your body produces continuously. It is the primary intracellular antioxidant and sits at the center of detoxification, immune signaling, and redox balance.

  • How do I use it?

    Instill 1-2 sprays in each nostril once daily. The approximate dose is 120 mg per day depending on usage.

  • How should I store it?

    Refrigerate after opening. Potency window is 60 days from first use. Cold-chain shipping keeps every bottle at peak potency on arrival.

  • How is this different from a glutathione capsule?

    Oral glutathione is largely degraded in the digestive tract before it reaches circulation — most studies show <10% absorption. Intranasal delivery bypasses first-pass metabolism, putting glutathione directly where it can work.

  • Are there side effects?

    Most people tolerate intranasal glutathione well. Some may experience mild, temporary nasal sensations during the first few uses.

  • How does this compare to the IV push?

    The IV push delivers a higher single-dose load in a 5-10 minute clinic appointment. The spray delivers a measured ~120 mg every day. They are complementary formats with different dosing and absorption profiles.

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