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Hydration Room RSM

Hydration Room Rancho Santa Margarita

22451 Antonio Pkwy, Suite A350
Rancho Santa Margarita, CA 92688
(949) 742-6798

HOURS

Mon - Fri: 8:30am-5:30pm
Sat - Sun: 9am-5pm
Closed for lunch 12:30pm-1:30pm every day.

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Clinic, Directions, and Parking Information

Directions: Hydration Room Rancho Santa Margarita is located off Antonio Parkway on the South side of the shopping center, near Pavilions.
Parking: Free parking is available anywhere in the Antonio Plaza Shopping Center.  

Become a Member, Start Saving Today

Invest in your well-being with our membership. Enjoy a monthly IV, 20% off additional services and a free B12 shot when you sign up.

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$149
Per Month
1 IV per month + perks

What to Expect on Your Visit

First-Time Patients

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Book an Appointment

The easiest way is to schedule your treatment online. You can also call us or simply walk into any of our locations (subject to availability).

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Nurse Practitioner Consultation

Before your appointment, you get a free phone consultation with one of our experienced nurse practitioners, who will help plan your wellness journey. They’ll review your symptoms, medical history, and any allergies to recommend the most effective treatment for your goals. Please watch your email after booking to schedule your consult.

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Check In

Please arrive 15 minutes early to your appointment and check in with the Wellness Coordinator. You should receive a new patient form via text or email prior to your appointment. If you have not already filled it out, you will need to once you arrive. 

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Review with Registered Nurse

Before receiving your treatment, you will briefly meet with one of our RNs in our private consult room. They will confirm your treatment and answer any questions. They will also administer your injection therapy (in the glutes) or your IV insertion.

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Treatment

If you are receiving IV therapy, you will go into the lounge room, where you can relax and sip tea or water while you receive your IV drip. IV therapy usually takes 35-45 minutes. Private rooms with TVs are available in some locations; call ahead to reserve one at no extra charge.

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Check Out

Our staff strives to make your wellness journey as pleasant and effective as possible. If you are happy with your experience, consider granting your treatment team a gratuity.

Returning Patients

Have you received treatment from us before? Just book your appointment online and arrive at your scheduled time. You’ll have a quick review with a registered nurse to ensure you get the best treatment for your goals. Ask about our membership plan for additional savings and perks.

Rancho Santa Margarita IV Therapy and Injections

Recharge, Hydrate, and Thrive. Need a refresh? Hydration Room’s IV therapy and vitamin injections deliver hydration, essential nutrients, and antioxidants directly into your system for optimal wellness. If you're looking to strengthen immunity, support workout recovery, or improve mental clarity, our customized treatments will help you feel your best. Visit us in Rancho Santa Margarita, CA.

Our IV and Injection Therapies

At Hydration Room, we offer physician-designed IV and injection therapies tailored to your unique health and wellness goals. Whether you need relief from migraines, jet lag, inflammation, or chronic fatigue, our targeted IV treatments are designed for rapid absorption and long-lasting benefits—so you can get back to doing what you love. View all Services.

Premier IV and Injection Therapies in Rancho Santa Margarita

Since 2014, Hydration Room has led the way in modern IV therapy, offering treatments that promote hydration, energy, and long-term wellness. Our proprietary IV formulas support immune function, metabolism, and recovery, making it easier to maintain peak health. With both in-clinic and mobile IV therapy services, we bring physician-designed wellness to Rancho Santa Margarita and surrounding areas

How IV Therapy Works

IV therapy is an efficient, effective way to restore hydration and replenish key nutrients that your body needs to function optimally. Unlike oral supplements, which take time to absorb, IV therapy delivers vitamins and minerals directly into the bloodstream for fast-acting results.

At our Rancho Santa Margarita location, our medical professionals ensure a relaxing, spa-like experience where you can unwind while recharging your body.

High-Quality Formulas, Backed by Science

Hydration Room’s IV and injection therapies are physician-developed and made with premium, pharmacy-grade ingredients. From immune-boosting antioxidants to metabolism-enhancing nutrients, our treatments are designed for maximum effectiveness and long-term wellness benefits.

Mobile IV Therapy in Rancho Santa Margarita – Wellness on the Go

Want IV therapy without leaving your home? Hydration Room offers mobile IV therapy in Rancho Santa Margarita, bringing hydration, recovery, and wellness support right to your doorstep. Whether you're at home, at work, or hosting an event, our mobile services ensure convenient, on-demand care when you need it most.