Hydration Room Rancho Santa Margarita
Mon - Fri: 8:30am-5:30pm
Sat - Sun: 9am-5pm
Closed for lunch 12:30pm-1:30pm every day.
Visit Our Rancho Santa Margarita Clinic
Phone
Hours
Mon - Fri: 8:30am-5:30pm
Sat - Sun: 9am-5pm
Closed for lunch 12:30pm-1:30pm every day.
Directions
Hydration Room Rancho Santa Margarita is located in Antonio Plaza off Antonio Parkway on the South side of the shopping center, near Pavilions.
Plaza
Antonio Plaza
Parking
Free parking is available anywhere in the Antonio Plaza Shopping Center.
Services Available at Our Rancho Santa Margarita Location
Cold & Flu Remedy
Immune Support
Wellness Infusion
Fitness Recovery
Skin Health
Myers Cocktail
Hangover (Basic)
Hangover (Deluxe)
Jet Lag
Stress Rescue
Happy Tummy
Glutathione
Celebration
Energy Boost
GI Cocktail
Vitamin C Boost
Maternity Wellness
Menopause Relief
Migraine Relief
Monthly Relief
Slim
Skinny Shot Injection
B12 Basic Boost Injection
Antioxidant Refresh Shot
Cold and Flu Boost Injection
Happy Shot
Anti-Stress Shot
Glutathione Shot
NAD+ IV
NAD+ Injection
Stem Cells & Exosomes
Iron Infusions
GLP-1 Injections
Testosterone Replacement Therapy (TRT)
Hormone Wellness Support
Chelation Therapy
Three Simple Steps to Feeling Better
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What to Know Before You Visit Our Rancho Santa Margarita Clinic
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Bring a valid photo ID
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Know your goals (energy, immunity, stress, etc.)
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Provide medical history or list of allergies
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Wear comfortable clothing
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Expect a 45–60 min session
Relax in Our Rancho Santa Margarita Wellness Clinic
Whether you're coming down from a hike at O'Neill Regional Park, wrapping up a round at Tijeras Creek, or unwinding after a night out at the Town Center, our clinic offers a quiet place to slow down and restore. Relax in comfortable seating while our licensed medical team reviews your goals and prepares the IV therapy tailored to you.
An individual treatment room is also available, subject to availability, if you prefer a more private session. You'll receive the same personalized, one-on-one care that Hydration Room is known for across Rancho Santa Margarita.
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Your Monthly Dose of Hydration, Energy & Recovery
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1 IV Per Month (Up to $230)
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20% off Additional IVs, Injections, and Add-Ons
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Free B12 Shot at Sign Up ($25 Value)
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Anniversary Award - Free Myers Cocktail IV ($195 Value)
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Redeem at Any Hydration Room Location
Trusted by Thousands of Patients
Rancho Santa Margarita IV Therapy and Injections
Rancho Santa Margarita's wellness culture blends the active, outdoor lifestyle of Orange County with a growing interest in holistic, preventive, and functional medicine. Between the trails, the lake, and a community that leans into high-tech fitness and recovery, residents here treat wellness as part of daily life. Our physician-formulated IV and injection therapies deliver targeted hydration, vitamins, and essential nutrients directly into the bloodstream to help support the energy and long-term health this pace demands.
Personalized IV and Injection Therapies
Our patients in Rancho Santa Margarita come in with a range of wellness needs. Some are recovering from a workout, others need a reset after a weekend at the lake or a night out, and many are simply managing the stress of a busy family or work schedule. Our licensed medical team takes the time to understand your specific goals and build a therapy around them, whether that's metabolic support, hangover recovery, overall vitality, or a session focused on stress management. View all treatments.How IV and Injection Therapy Works
Oral supplements have to be digested before your body can absorb them. IV therapy delivers hydration and nutrients directly into the bloodstream for faster, more complete absorption. See how they compare below.
|
Factor |
IV Therapy at Hydration Room |
Oral Supplements |
|
Absorption Rates |
Near-complete, directly into the bloodstream |
Estimated 2-20% (gut-dependent) |
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GI Side Effects |
Bypasses the gut, minimal impact |
Nausea, constipation, and cramping are common |
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Works With GI Absorption Issues |
Yes, bypasses the gut entirely |
No, depends on gut function |
|
Speed of Delivery |
Immediate entry into the bloodstream |
Slow; digestion and absorption are required |
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Medical Oversight |
Physician-formulated, team on-site |
Self-administered |
|
Best For |
Guests needing reliable, fast iron replenishment without GI side effects |
Mild ongoing supplementation with good gut health |
Discover Rancho Santa Margarita Hydration Room
Founded in 2014 by Dr. Brett Florie, Board-Certified Anesthesiologist, Hydration Room has been delivering physician-developed IV and injection therapies for over a decade. Our Rancho Santa Margarita clinic, located in Antonio Plaza, uses the same physician-formulated protocols and premium-grade ingredients available at all 50+ Hydration Room locations across California.
We proudly serve residents across Rancho Santa Margarita and the surrounding area, including Mission Viejo, Coto de Caza, Trabuco Canyon, and Las Flores.
Frequently Asked Questions
Yes! You are welcome to bring a friend or family member. Many of our local guests find that sharing the experience makes the session more relaxing.
Ready to Feel Your Best?
injection therapy or IV hydration at Hydration Room Rancho Santa Margarita!